Here, we show that functionalization of the 4-arylidene position of the fluorescent curcumin scaffold with an aryl nitrogen mustard provides a stable Hck inhibitor (Kd = 50 ± 10 nM). The mustard curcumin derivative preferentially interacts with the inactive conformation of Hck, similar to type-II kinase inhibitors that are less promiscuous. Moreover, the lead compound showed no inhibitory effect on three other kinases (DYRK2, Src, and Abl). We demonstrate that the cytotoxicity may be mediated via

Тема Светлая Темная Высокая контрастность

Однако во срок очередного эксперимента произошел взрыв, как и ученый получил значительную дозу радиации сам. С тех пор каждый раз, когда его пульс превышает определенную отметку, спокойный пантелеймон превращается в огромного, зеленого, неуправляемого монстра, за которым охотится обеспокоенное правительство… Рано или поздно вы ищете увлекательный, но неглупый боевик, то разглядывать онлайн «Халк» - это ваше решение!

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Original: I ordered the 8 piece bone in with Carolina Reaper sauce on the chicken. I requested the chicken be cooked well done. It was a combo with fries. The fries were cooked perfect and seasoned. The chicken was raw. Out of the 8 piece I could safely eat 2 pieces. As a cook, you know the texture of fine chicken versus underdone. The fact I asked in the comment section of my grub hub order to cook the chicken well, maybe I upset the chef because I got a $16+ box of raw chicken.

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Ослепляющий камуфляж: сколько спрятать корабль в открытом море.

The wings were excellent and fries were cooked just right. I couldn't skip the chicken sandwich either which was juicy and breaded jist right. I can't wait to return and try the chicken and waffles.

Клиент должен быть уникальным; вы не можете заключать в себе диски.

В этом случае рекомендуется получить полный список тестов:

Krinkle Kut hand tossed fries, cheddar cheese, chopped hand-breaded chicken in your choice of sauce or country style and then drizzled with GOOD sauce

In addition to the above JAKIM recognizes reputable and credible foreign Halal certification bodies as JAKIM representatives to monitor/verify the halal status of these raw materials and products with responsibility and integrity. The recognition is based on the capability of the foreign halal certification bodies to comply with the Malaysian procedures & guidelines. HQC is officially accredited and recognized from JAKIM-Malaysia.

Необходимо указать только один параметр. когда параметр не указан или указан несколько параметров, вы получите ошибку.

Мужчина шел по улице как и услышал странный стон, доносящийся просто из-под земли. Недолго думая, он начал разбирать тротуарную плитку